Edit Cancer Cells with CRISPR/Cas9

Deze masterclass zal online worden gegeven. 

Can you imagine the many things we could do by editing a specific part of the DNA? We could cure many diseases, discover new gene functions or even grow bigger crops to increase food production. The good news is that we are now closer than ever to achieve this thanks to CRISPR/Cas9, a genome editing tool that allows scientists to edit DNA in an easy, cheap and specific way. If you want to learn more about this fascinating technique that is revolutionizing the whole world with its incredible potential, then this is a Masterclass for you!

By joining this online Masterclass, you will gain deeper knowledge of the CRISPR/Cas9 technique and you will have the opportunity to work in a virtual laboratory. You will learn about the (Epithelial-Mesenchymal) transition certain cancer cells can undergo which causes them to become mobile and able to colonize different organs (metastasize). You will visualize the proteins E-cadherin and F-actin, who’s changes mark the transition. By using CRISPR/Cas9, you will be able to see the effect on these two proteins when editing genes associated with the transition. The ultimate goal? To better understand the factors that enable a cell to metastasize.

Thus, you will experience working in a virtual lab and you will learn about a technique that more scientists are introducing to their labs every day! In addition, during the online Masterclass, you will have the chance to interact and learn from fellow students and teachers from the UMC Utrecht.

This masterclass will be presented in English, but a Dutch person will be present so it will be possible to ask questions in Dutch. Note that for this Masterclass it is necessary that you have read the DNA chapter of your school book. If you haven’t, we strongly advise you to ask for your teacher’s help and carefully read through it.

Deze masterclass is voor 5 of 6 vwo’ers met biologie.


Bij deze masterclass zit een voorbereidende opdracht van 4 uur.

Praktische informatie

5 vwo 6 vwo
Vrijdag 5 maart 2021
Online via Microsoft Teams
Ambitie Connectie Open
Gratis, alleen toegankelijk voor leerlingen van onze partnerscholen


U-Talent coördinatoren kunnen leerlingen aanmelden via een inschrijfformulier dat te vinden is op de pagina over de masterclasses-inschrijving. Hier vind je ook alle deadlines en informatie over (de spelregels rondom) het plaatsen van leerlingen.

Online masterclasses zijn alleen toegankelijk voor leerlingen van onze partnerscholen.

Lees hier onze algemene voorwaarden en privacyverklaring.

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